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The enzymes responsible for the production of ROS and RNS have been unravelled and the participation of these species in numerous signalling pathways has been documented. The next step is now to identify the targets of ROS and RNS and the mechanisms by which they alter their activity in the affected signalling pathway and significant progress has already been made. This exciting area of research will benefit from the pulling together of the work from hard-core chemists and free radical aficionados along with that of signalling enthusiasts and cell biologist devotees. This was the idea behind the conception of this new book. | ||
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